Format

Send to

Choose Destination
Scand J Gastroenterol. 1996 Nov;31(11):1047-51.

Gastroesophageal reflux in obese patients is not reduced by weight reduction.

Author information

1
Dept. of Surgery, Ersta Hospital, Stockholm, Sweden.

Abstract

BACKGROUND:

The present study tested the hypothesis that weight reduction improves the subjective and objective manifestations of gastroesophageal reflux.

METHODS:

Twenty obese patients with gastroesophageal reflux as shown by 24-h pH measurement and with symptoms requiring daily medication were studied. The patients were randomized into a group (A) treated with very low-caloric diet (VLCD) and a control group (B). Objective measurements were repeated after 6 months. Group B was then treated with VLCD and reexamined.

RESULTS:

Patients in group A lost 10.8 +/- 1.4 kg whereas group B gained 0.6 +/- 0.7 kg (P < 0.001). There was no reduction in reflux according to pH measurement. Furthermore, there were no significant changes in reflux symptoms. After VLCD treatment, group B lost 9.7 +/- 1.6 kg, but reflux indicators remained unchanged. All patients except one in group B remained dependent on daily anti-reflux medication.

CONCLUSION:

Weight reduction does not improve the subjective or objective manifestations of reflux.

PMID:
8938895
[Indexed for MEDLINE]

Supplemental Content

Loading ...
Support Center