Format

Send to

Choose Destination
J Bacteriol. 1996 Nov;178(22):6618-22.

Eukaryotic interference with homoserine lactone-mediated prokaryotic signalling.

Author information

1
Department of Microbiology, The Technical University of Denmark, Lyngby.

Abstract

Acylated homoserine lactones (AHLs) play a widespread role in intercellular communication among bacteria. The Australian macroalga Delisea pulchra produces secondary metabolites which have structural similarities to AHL molecules. We report here that these metabolites inhibited AHL-controlled processes in prokaryotes. Our results suggest that the interaction between higher organisms and their surface-associated bacteria may be mediated by interference with bacterial regulatory systems.

PMID:
8932319
PMCID:
PMC178549
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for HighWire Icon for PubMed Central
Loading ...
Support Center