Send to

Choose Destination
Ultramicroscopy. 1996 Jul;63(3-4):205-18.

A common-lines based method for determining orientations for N > 3 particle projections simultaneously.

Author information

Wadsworth Center for Laboratories and Research, New York State Department of Health, Albany 12201-0509, USA.


A method is proposed for determining the directions of projections. An arbitrary number of projections of unknown three-dimensional structure are simultaneously used as input. The method is based on common lines and uses a new discrepancy measure accounting for the uneven distribution of common lines in angular space. An application to the 70S Escherichia coli ribosome data obtained from an energy-filtering electron microscope is described.

[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center