Inactivation of tryptic activity by a human-derived strain of Bacteroides distasonis in the large intestines of gnotobiotic rats and mice

F Ramare; I Hautefort; F Verhe; P Raibaud; J Iovanna

doi:10.1128/aem.62.4.1434-1436.1996

Inactivation of tryptic activity by a human-derived strain of Bacteroides distasonis in the large intestines of gnotobiotic rats and mice

Appl Environ Microbiol. 1996 Apr;62(4):1434-6. doi: 10.1128/aem.62.4.1434-1436.1996.

Authors

F Ramare¹, I Hautefort, F Verhe, P Raibaud, J Iovanna

Affiliation

¹ Unité d'Ecologie et Physiologie du Système Digestif, Centre de Recherches de Jouy en Josas, France.

Abstract

Tryptic activity disappeared and trypsin was no longer detected with an antitrypsin antiserum in the large intestines of gnotobiotic rats and mice monoassociated with a human-derived strain of Bacteroides distasonis, whereas tryptic activity was not modified in the small intestines. This function was shown to be strain specific.

MeSH terms

Animals
Antibodies
Bacteroides / isolation & purification
Bacteroides / metabolism*
Germ-Free Life
Humans
Intestine, Large / enzymology
Intestine, Large / microbiology
Intestine, Small / enzymology
Intestine, Small / microbiology
Mice
Mice, Inbred C3H
Rats
Rats, Inbred F344
Trypsin / immunology
Trypsin / metabolism*
Trypsin Inhibitors / metabolism

Substances

Antibodies
Trypsin Inhibitors
Trypsin