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Retina. 1996;16(5):383-7.

Recurrent ocular toxoplasmosis in patients treated with systemic corticosteroids.

Author information

1
UCLA Ocular Inflammatory Disease Center, Jules Stein Eye Institute 90095-7003, USA.

Abstract

PURPOSE:

The authors discuss a possible relationship between systematic corticosteroid use and reactivation of ocular toxoplasmosis.

METHODS:

Patients were identified who developed foci of recurrent toxoplasmic retinochoroiditis while being treated with systemic corticosteroids. Case histories were reviewed retrospectively.

RESULTS:

During a 10-year interval, three patients were identified at the University of California, Los Angeles, who had been receiving systemic corticosteroid therapy (dose range, 0.27-1.23 mg/kg/day) when they developed recurrent toxoplasmic retinochoroiditis. Disease occurred at intervals of 20 days to approximately 1 year after start of corticosteroid therapy. Lesions were typical in appearance, course, and manner in which they responded to antimicrobial therapy.

CONCLUSION:

Recurrent toxoplasmosis in patients receiving corticosteroid therapy probably is uncommon. These cases do not confirm a causal relationship between corticosteroid use and initiation of disease recurrence.

PMID:
8912963
[Indexed for MEDLINE]

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