Format

Send to

Choose Destination
J Nat Prod. 1996 Oct;59(10):994-6.

Chlorinated annonaceous acetogenins and their bioactivities.

Author information

1
Department of Medicinal Chemistry and Molecular Pharmacology, School of Pharmacy and Pharmacal Sciences, Pardue University, West Lafayette, Indiana 47907, USA.

Abstract

4(S)-Chloro-4-deoxygigantetrocin A and 4(S), 18-dichloro-4,18-dideoxyasimilobin were obtained by treating gigantetrocin A with triphenylphosphine and CCl4. The structures were determined by spectroscopic methods. The chlorinated compounds show decreased bioactivities in the brine shrimp lethality test and against human tumor cell lines.

PMID:
8904848
DOI:
10.1021/np9605089
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for American Chemical Society
Loading ...
Support Center