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Emerg Infect Dis. 1996 Jul-Sep;2(3):176-82.

Conjugate vaccines and the carriage of Haemophilus influenzae type b.

Author information

1
John Radcliff Hospital, Oxford, England. hughes@rmplc.co.uk

Abstract

Pharyngeal carriage of Haemophilus influenzae type b (Hib) is important in the transmission of Hib organisms, the pathogenesis of Hib disease, and the development of immunity to the bacterium. The remarkable success of current vaccination programs against Hib has been due in part to the effect of conjugate Hib vaccines in decreasing carriage of Hib. This review explores evidence for this effect, and discusses the possible mechanisms of the mucosal influence of Hib conjugate vaccines.

PMID:
8903227
PMCID:
PMC2626802
DOI:
10.3201/eid0203.960303
[Indexed for MEDLINE]
Free PMC Article

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