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Curr Opin Immunol. 1996 Oct;8(5):688-93.

The Th1/Th2 paradigm and the allograft response.

Author information

1
Department of Medicine, Harvard Medical School, Beth Israel Hospital, Boston, MA 02115, USA. tstrom@bih.harvard.edu

Abstract

Although Th1- and Th2-type cytokine profiles have been associated with rejection and tolerance respectively, this paradigm may not be completely accurate. Instead, recent studies suggest that there could be a hierarchy of T-cell growth factors with regard to their ability to block tolerance and induce rejection (rather than a polarized Th1/Th2 demarcation).

PMID:
8902395
DOI:
10.1016/s0952-7915(96)80087-2
[Indexed for MEDLINE]

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