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Mol Biol Rep. 1995-1996;22(2-3):125-9.

RNase P RNA of Mycoplasma capricolum.

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Department of Biology, Faculty of Science, Hirosaki University, Japan.


There are at least six small stable RNAs in Mycoplasma capricolum cells besides tRNAs and rRNAs. One of them, MCS5 RNA, is a homolog of RNase P RNA. The predicted secondary structure of this RNA is essentially the same as that of other eubacterial RNase P RNAs. MCS5 RNA is more similar to the RNase P RNA of B. Subtilis than to that of E. coli. This is consistent with previous conclusions that mycoplasmas are phylogenetically related to the low G + C Gram-positive bacterial group. The major substrates for MCS5 RNA must be the precursors of tRNAs. The precursor of MCS6 RNA, which is a homolog of the E. coli 10Sa RNA, may also be a substrate for the MCS5 RNA because this RNA has a tRNA-like structure at its 5' and 3' ends.

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