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Psychiatry Res. 1996 Aug 30;64(1):69-75.

Personality disorders in first- and multiple-episode mania.

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  • 1Department of Psychiatry, University of Cincinnati College of Medicine, OH 45267-0559, USA.


We compared rates of DSM-III-R personality disorders in 33 first-episode and 26 multiple-episode bipolar patients. Patients were evaluated with the patient and personality disorders versions of the Structured Clinical Interview for DSM-III-R. Significantly more multiple-episode patients (65%) met DSM-III-R criteria for a personality disorder than did first-episode patients (33%). Race was also associated with a diagnosis of a personality disorder. Personality disorders may be associated with multiple affective episodes in bipolar patients.

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