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Obstet Gynecol. 1996 Nov;88(5):792-6.

Salivary progesterone concentrations after tubal sterilization.

Author information

1
Department of Obstetrics and Gynecology, University of Turku, Finland.

Abstract

OBJECTIVE:

To find out if ovarian endocrine function is hampered by laparoscopic tubal sterilization.

METHODS:

Salivary progesterone levels were measured in 55 women undergoing a laparoscopic tubal sterilization with Hulka or Filshie clips. The participants were 31-43 years old (mean 37) and were menstruating regularly. The saliva was collected every morning during three menstrual cycles: on the cycle preceding sterilization, and 3 and 12 months after the procedure. Salivary progesterone levels were determined by a radioimmunoassay.

RESULTS:

Total progesterone secreted in the luteal phase declined slowly after the sterilization, resulting in the lowest values 1 year after the procedure (1780 +/- 807 versus 2431 +/- 1187 pmol/L before surgery, P = .001). The luteal peak progesterone values were lowest 3 months after sterilization (277 +/- 137 pmol/L). Although the peak progesterone secretion seemed to have started to recover at 12 months (318 +/- 171 pmol/L), it was still significantly less than before surgery (378 +/- 150 pmol/L, P = .015). The length of the entire menstrual cycle and the lengths of the follicular and luteal phases were not affected.

CONCLUSION:

Although the menstrual pattern was not affected, laparoscopic tubal sterilization caused measureable changes in the luteal function. However, these changes may be temporary in nature.

PMID:
8885915
DOI:
10.1016/0029-7844(96)00287-6
[Indexed for MEDLINE]

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