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J Nat Prod. 1996 Mar;59(3):293-6.

Metabolites from an Antarctic sponge-associated bacterium, Pseudomonas aeruginosa.

Author information

1
Department of Chemistry, Florida Institute of Technology, Melbourne 32901, USA.

Abstract

In an ongoing survey of the bioactive potential of microorganisms associated with marine invertebrates, the culture media of a sponge-associated bacterial strain of Pseudomonas aeruginosa was found to contain metabolites which inhibit the growth of several Gram-positive microorganisms. A series of diketopiperazines (1-6) including a new natural product (6) and two known phenazine alkaloid antibiotics (7 and 8) were isolated from the culture broth of this bacterium.

PMID:
8882433
DOI:
10.1021/np960095b
[Indexed for MEDLINE]

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