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Trends Biochem Sci. 1996 May;21(5):164-5.

Extraribosomal functions of ribosomal proteins.

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Department of Biochemistry and Molecular Biology, The University of Chicago, IL 60637, USA.


The discovery of DNA-binding motifs in ribosomal proteins has led to the conjecture that the transition of the ribosome from an RNA to an RNP machine occurred by adding pre-existing proteins. Supportive, but circumstantial, evidence for the hypothesis is adduced from the finding that many ribosomal proteins have a second function apart from the particle. These extraribosomal functions are enumerated.

[Indexed for MEDLINE]

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