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Comput Chem. 1996 Mar;20(1):119-21.

CENSOR--a program for identification and elimination of repetitive elements from DNA sequences.

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Linus Pauling Institute of Science and Medicine, Palo Alto, CA 94306, USA.


CENSOR is a program designed to identify and eliminate fragments of DNA sequences homologous to any chosen reference sequences, in particular to repetitive elements. CENSOR is based on two principal algorithms of Smith & Waterman (1981) [J. Mol. Biol. 147, 195] and Wilbur & Lipman (1983) [Proc. Natl. Acad. Sci. U.S.A. 80, 726]. It includes several pre-set sensitivity levels based on both biological and statistical criteria which help to distinguish between aligned pairs of homologous and non-homologous sequences. CENSOR has been implemented in C/C + + in the SUN/UNIX environment.

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