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J Urol. 1996 Nov;156(5):1631-2.

The efficacy of fluoxetine in the treatment of premature ejaculation: a double-blind placebo controlled study.

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1
Department of Psychiatry, Medical School of Yüzüncü Yil University, Van, Turkey.

Abstract

PURPOSE:

The efficacy of the selective serotonin re-uptake inhibitor fluoxetine in the treatment of premature ejaculation was examined.

MATERIALS AND METHODS:

The study comprised 17 patients with premature ejaculation who presented to the urology clinic of our medical school. In this double-blind study the patients were randomized into treatment groups receiving 20 mg. fluoxetine daily for 1 week and 40 mg. daily afterward (group 1) or 1 capsule placebo daily for 1 week and 2 capsules daily afterward (group 2). The groups were evaluated according to the latent period of intravaginal ejaculation.

RESULTS:

The latent period of intravaginal ejaculation in group 1 was significantly longer than that in group 2. Nausea, headache and insomnia were reported side effects.

CONCLUSIONS:

Fluoxetine may be regarded as a safe and effective alternative in the treatment of premature ejaculation.

PMID:
8863556
[Indexed for MEDLINE]
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