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Vet Microbiol. 1996 Mar;49(1-2):147-52.

Canine distemper virus infection in Serengeti spotted hyenas.

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Institute for Virology, Veterinary School, Hannover, Germany.


Clinical signs suggestive of canine distemper virus (CDV) infection were observed among a group of spotted hyenas (Crocuta crocuta) in the Serengeti, Tanzania. Virus antigen was detected immunohistologically in a brain sample from a diseased cub. The presence of virus RNA could be demonstrated in this brain as well as in intestine and lymph node of the animal by RT-PCR. Sequence comparison of brain-derived amplicons showed that the virus was related to recent CDV field isolates. The closest homology (>99 percent) was to a recently described CDV which caused high mortality in sympatric lions.

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