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Trends Microbiol. 1996 Aug;4(8):307-12.

DNA immunization.

Author information

1
Dept of Neuropharmacology, Scripps Research Insitute, La Jolla, CA 92037, USA.

Abstract

Inoculation with plasmid DNA vectors encoding immunogenic proteins induces both humoral and cell-mediated immune responses, which often provide protective immunity. Although many questions regarding the mechanism, efficacy and safety of DNA immunization remain to be addressed, this approach may offer a safer and more cost-effective alternative to conventional vaccines.

PMID:
8856868
DOI:
10.1016/0966-842x(96)10048-2
[Indexed for MEDLINE]

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