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Trends Genet. 1996 Feb;12(2):69-74.

Mating systems in ascomycetes: a romp in the sac.

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Department of Biology, University of New Mexico, Albuquerque 87131, USA.


The ascomycetous fungi choose between sexual and asexual reproduction; it is only when appropriately stressed that most resort to sexual development. Many of the proteins known to regulate development in animals (homeodomain proteins, HMG-box proteins) are also central to the control of sexual differentiation in the ascomycetes. Most ascomycete mating-type loci are structurally complex idiomorphs (large regions of nonhomologous DNA), in that they encode multiple products of probable independent evolutionary origin. The products of the mating-type genes are the master regulators of sexual development; we are just beginning our search for factors involved in the signal transduction pathway downstream from these master regulators.

[Indexed for MEDLINE]

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