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Trends Genet. 1996 Feb;12(2):58-62.

Deviant nucleosomes: the functional specialization of chromatin.

Author information

1
Laboratory of Molecular Embryology, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892-2710, USA. awlme@helix.nib.gov

Abstract

Regulatory proteins exist with strong sequence and structural similarities to the histone proteins. Molecular genetic and cell biological analyses suggest that these proteins are localized at particular sites within the chromosome. Their assembly into nucleosomal structures confers specialized functions to individual chromosomal domains.

PMID:
8851972
DOI:
10.1016/0168-9525(96)81401-6
[Indexed for MEDLINE]

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