Disseminated histoplasmosis followed by disseminated coccidioidomycosis

Chest. 1977 Aug;72(2):238-41. doi: 10.1378/chest.72.2.238.

Abstract

A case of disseminated histoplasmosis followed later by disseminated coccidioidomycosis is described. The clinical illness and immunologic studies suggest subtle defects that may have existed antecedent to infection and, thus, provided an opportunity for widespread dissemination by these normally nonopportunistic organisms. Poor correlation was noted between the clinical course and in vitro tests of cell-mediated immunity.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Amphotericin B / therapeutic use
  • Coccidioides / isolation & purification
  • Coccidioidomycosis / complications*
  • Coccidioidomycosis / drug therapy
  • Coccidioidomycosis / immunology
  • Complement Fixation Tests
  • Histoplasma / isolation & purification
  • Histoplasmosis / complications*
  • Histoplasmosis / drug therapy
  • Histoplasmosis / immunology
  • Humans
  • Lymphocyte Activation
  • Male
  • Precipitins / analysis
  • Skin Tests

Substances

  • Precipitins
  • Amphotericin B