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J Psychosom Res. 1996 Jun;40(6):625-35.

Empirical psychological modeling of chest pain: a comparative study.

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Erasmus University Rotterdam, Department of Medical Psychology and Psychotherapy, The Netherlands.


In this study the psychological profiles of 67 patients with noncardiac chest pain (NCA) and 47 patients with coronary artery disease (CAD) were analyzed to construct an empirical-psychological model that would be able to discriminate these two groups. All patients were suffering from chest pain at the time of referral by their general practitioner. The noncardiac patients were significantly younger, more often female, single, and nonsmokers. The two groups differed significantly on anxiety, somatization, obsessive compulsive behavior, psychoneuroticism, and hyperventilation. Logistic regression analysis on the variables jointly, showed that age, gender, anxiety, and hyperventilation contributed significantly to the model for discriminating between the two groups. Crossvalidation showed that the constructed model was stable.

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