Format

Send to

Choose Destination
See comment in PubMed Commons below
Genomics. 1996 Feb 1;31(3):301-10.

CONTIG EXPLORER: interactive marker-content map assembly.

Author information

1
Center for Medical Informatics, Yale School of Medicine, New Haven, Connecticut 06520, USA. nadkarni@cs.yale.edu

Abstract

In STS-content mapping of a region, multiple optimal or near-optimal putative orders of markers exist. Determining which of the markers in this region can be placed reliably on the physical map of the chromosome and which markers lack sufficient evidence to be placed requires software that facilitates exploratory sensitivity analysis and interactive reassembly with different subsets of the imput data and that also assists the evaluation of any arbitrary (user-specified) marker order. We describe CONTIG EXPLORER, a package for interactive assembly of STS-content maps that provides the user with various ways of performing such analyses, thereby facilitating the design of laboratory experiments aimed at reducing ambiguity in STS order. We then compare the output of CONTIG EXPLORER with two other assembly programs, SEGMAP and CONTIGMAKER, for a region of chromosome 12p between 21 and 38 cM on the sex-averaged CEPH/Généthon linkage map.

PMID:
8838311
DOI:
10.1006/geno.1996.0052
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Support Center