Send to

Choose Destination
J Am Coll Nutr. 1996 Aug;15(4):340-4.

Zinc and growth.

Author information

Department of Pediatrics, Hiroshima Red Cross Hospital, Japan.


Zinc is an essential nutrients and plays an important role in growth and sexual function. Zinc deficiency has been known to cause growth retardation and hypogonadism. Several mechanisms of growth retardation and hypogonadism due to zinc deficiency have been suggested. Zinc affects growth hormone (GH) metabolism. Conversely, GH affects zinc metabolism. Zinc deficiency may result in reduced GH production and/or insulin-like growth factor-I (IGF-I). Zinc deficiency may also affect bone metabolism and gonadal function. The interrelationships among zinc, growth, gonadal function, and GH-IGF-I axis appears to be complex.

[Indexed for MEDLINE]

Supplemental Content

Loading ...
Support Center