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Immunol Today. 1996 Mar;17(3):138-46.

The expanding universe of T-cell subsets: Th1, Th2 and more.

Author information

1
Department of Medical Microbiology and Immunology, University of Alberta, Edmonton, Canada. tim.mosmann@ualberta.ca

Abstract

Since their discovery nearly ten years ago, T helper 1 (Th1) and Th2 subsets have been implicated in the regulation of many immune responses. In this article, Tim Mosmann and Subash Sad discuss the increasing number of T-cell subsets defined by cytokine patterns; the differentiation pathways of CD4+ and CD8+ T cells; the contribution of other cell types to these patterns; and the cytokine interactions during infection and pregnancy.

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PMID:
8820272
[Indexed for MEDLINE]

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