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Nutr Rev. 1996 Jun;54(6):178-80.

Beta-carotene increases lung cancer incidence in cigarette smokers.

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1
Differentiation Control Section, National Cancer Institute, Bethesda, MD 20892-4255, USA.

Abstract

Clinical trials were designed to validate the protective effect of beta-carotene in populations of cigarette smokers at high risk for lung cancer development. Strikingly, an increase in lung cancer resulted following beta-carotene supplementation in two separate studies in Finland and the United States. These trials were conducted without any evidence that beta-carotene prevents lung cancer in animal models.

PMID:
8810825
[Indexed for MEDLINE]
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