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FEMS Microbiol Lett. 1996 Sep 1;142(2-3):155-60.

Role of ribosome degradation in the death of heat-stressed Salmonella typhimurium.

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Department of Microbiology, University of Denmark, Lyngby, Copenhagen, Denmark.


Heat treatment of Salmonella typhimurium results in cell death, which coincides with a significant reduction of the cellular content of 16S ribosomal RNA. It is suggested that the degradation of ribosomal RNA is a direct cause of cell death. This conclusion is based on the observation of carbon-starved and magnesium-supplemented cells, which survive heat treatment much better, and which also maintain stable levels of ribosomal RNA.

[Indexed for MEDLINE]

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