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Clin Exp Rheumatol. 1996 May-Jun;14(3):289-93.

Weight reduction in obese patients with rheumatoid arthritis, with preservation of body cell mass and improvement of physical fitness.

Author information

1
Department of Medicine TA, Section of Rheumatology, Rigshospitalet, Copenhagen, Denmark.

Abstract

OBJECTIVE:

To reduce body weight in obese patients with rheumatoid arthritis (RA) without loss of body cell mass (BCM) and without impairment of physical performance.

METHODS:

Nineteen overweight RA patients were studied before, during, and after a 12-week weight reducing regime consisting of reduced dietary energy intake, supplemented with a high-protein-low-energy powder preparation, and moderate physical training. Body composition was measured by a four compartment method, which by combining determinations of total body water and total body potassium allows a distinction between the two variable components of fat free mass (FFM): BCM and extracellular water (ECW). Physical fitness was measured by a bicycle exercise test.

RESULTS:

Mean weight loss during the study was 4.5 kg. The patients lost 9% of their initial fat mass, 3% of initial BCM and 5% of initial ECW. Physical fitness was slightly, but significantly, improved.

CONCLUSION:

The regime described was successful in achieving a significant weight loss with minimal loss of BCM and maintenance of physical fitness.

PMID:
8809443
[Indexed for MEDLINE]
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