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Chem Biol. 1996 Jun;3(6):415-8.

Double agent: translational regulation by a transcription factor.

Author information

1
Department of Cell Biology, The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.

Abstract

The homeodomain protein bicoid activates transcription of several target genes by binding to target sequences in DNA. It has recently been shown that bicoid is also an RNA-binding protein that regulates the translation of caudal mRNA. Several ways for a protein to acquire dual functions can be imagined.

PMID:
8807871
DOI:
10.1016/s1074-5521(96)90088-5
[Indexed for MEDLINE]
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