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Curr Biol. 1996 Sep 1;6(9):1067-9.

Go outside and see the proteasome. Protein degradation.

Author information

1
Department of Biological Sciences, University of Warwick, Coventry CV4 7AL, UK.

Abstract

Newly synthesized proteins that fail to fold or assemble properly in the endoplasmic reticulum are degraded. Recent work on several endoplasmic reticulum membrane proteins has shown that the cytosolic proteasome plays a role in their degradation.

PMID:
8805359
DOI:
10.1016/s0960-9822(02)70666-0
[Indexed for MEDLINE]
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