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Curr Biol. 1996 Aug 1;6(8):962-4.

Keeping the centrosome cycle on track. Genome stability.

Author information

1
Department of Molecular, Cellular and Developmental Biology, University of Colorado at Boulder, Campus Box 347, Boulder, 80309-0347, USA.

Abstract

The protein kinase Mps1 and p53 both function in centrosome duplication and the spindle cell-cycle checkpoint. Defects in these functions can be potent sources of genomic instability by allowing mitosis to proceed with aberrant mitotic spindles.

PMID:
8805324
[Indexed for MEDLINE]
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