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Eur J Immunogenet. 1996 Jun;23(3):235-40.

HLA-DPB1 polymorphism in seven South American Indian tribes in Colombia.

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Department of Human Genetics, University of Newcastle upon Tyne, UK.


HLA-DPB1 allele frequencies were investigated in seven geographically and linguistically distinct Amerindian tribes of Colombia. Allele *1301 was found only in the Embera tribe living along the Pacific coast, while allele *0101 was found only in two individuals of the Wayuu tribe inhabiting the Guajira desert. Significant geographical variation was observed in the other two alleles (*1401 and *0402), which were found in all seven tribal groups. The possible reasons for this restricted polymorphism and the genetic diversity found in the investigation are discussed.

[Indexed for MEDLINE]

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