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Curr Opin Neurobiol. 1996 Feb;6(1):57-63.

The role of positive and negative signals in somite patterning.

Author information

1
Department of Biological Chemistry, Harvard Medical School, Boston, Massachusetts 02115, USA. lassarab@warren.med.harvard.edu

Abstract

Signals from the axial tissues, neural tube and notochord play a crucial role in patterning cell fates in adjacent somitic tissue. Work over the past four decades has indicated how signals from the axial tissues, as well as the surface ectoderm and lateral plate mesoderm, together act to pattern somitic cell fate. Furthermore, recent results have shed light on how some of these molecules control the specification and migratory behaviour of somitic cells.

PMID:
8794041
DOI:
10.1016/s0959-4388(96)80009-2
[Indexed for MEDLINE]

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