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Curr Opin Immunol. 1996 Aug;8(4):484-91.

Immunology of papillomavirus infection.

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Centre for Immunology and Cancer Research, University of Queensland, Princess Alexandra Hospital, Brisbane 4012, Australia.


Studies of the immunology of papillomavirus infection have come of age. Synthetic virus-like particles have been validated as vaccines for several animal papillomaviruses, and have been used to map the sero-epidemiology of human papillomavirus infection and to define papillomavirus neutralizing antibodies. Induction of cell-mediated immunity to papillomavirus early proteins is poised to become a therapeutic approach to papillomavirus infection. Studies on the immune response to papillomavirus proteins in keratinocytes are shedding light on the immunological consequences of antigen presentation by epithelial cells.

[Indexed for MEDLINE]

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