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Curr Biol. 1996 Jun 1;6(6):668-71.

Intracellular signalling: putting JAKs on the kinase MAP.

Author information

1
Molecular Biology & Virology Laboratory, Salk Institute for Biological Studies, La Jolla, California 92037, USA.

Abstract

Tyrosine kinases of the JAK family are required for activation of both STAT transcription factors and the ERK/MAP kinase pathway, suggesting a mechanism for the optimization of gene induction via the coordinate activation of multiple transcription factors.

PMID:
8793290
DOI:
10.1016/s0960-9822(09)00445-x
[Indexed for MEDLINE]
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