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Curr Opin Cell Biol. 1996 Feb;8(1):49-55.

Spectrin: on the path from structure to function.

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Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138, USA.


New structural analyses of the spectrin family of actin cross-linking proteins are providing molecular explanations for both the interchain binding between the alpha and beta chains of spectrin and the intermolecular associations between spectrin and other proteins. Additionally, the analyses bring into focus a conformation which may explain aspects of spectrin's interaction with lipids.

[Indexed for MEDLINE]

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