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Curr Opin Biotechnol. 1996 Apr;7(2):223-30.

Ex vivo culture systems for hematopoietic cells.

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  • 1Department of Chemical Engineering, Northwestern University, 2145 Sheridan Road, Evanston, Illinois 60208-3120, USA.


During the past few years, hematopoietic cell culture technologies for transplantation therapies have progressed significantly on several fronts. Advances include the discoveries of the growth factors thrombopoietin and Flt-3 ligand, the development of a variety of bioreactor systems, and results from preliminary clinical trials that demonstrate the efficacy of ex vivo expanded hematopoietic cells for transplantation therapy.

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