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Nat Struct Biol. 1996 Sep;3(9):747-52.

The hairpin stack fold, a novel protein architecture for a new family of protein growth factors.

Abstract

The granulin/epithelin protein motif has an unusual structure consisting of a parallel stack of beta-hairpins stapled together by six disulphide bonds. The new structure also contains a folding subdomain shared by small toxins, protease inhibitors as well as the EGF-like protein modules.

PMID:
8784346
DOI:
10.1038/nsb0996-747
[Indexed for MEDLINE]

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