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Pediatr Pulmonol. 1996 Jan;21(1):62-4.

Pulmonary alveolar microlithiasis in childhood: diagnosis by transbronchial biopsy.

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Respiratory Medicine Unit, Great Ormond Street Hospital for Children NHS Trust, London, UK.


A 7-year-old girl of Arabic origin by consanguineous parents presented with a miliary pattern on chest x-ray. Transbronchial lung biopsy revealed a histological diagnosis of pulmonary alveolar microlithiasis, a condition rarely described in childhood. This report highlights the clinical and radiological features, documents the transbronchial lung biopsy as a useful diagnostic procedure, and suggests a possible genetic etiology with autosomal recessive inheritance.

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