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J Pediatr. 1996 Aug;129(2):306-8.

Direct enzymatic assay of urinary sulfated bile acids to replace serum bilirubin testing for selective screening of neonatal cholestasis.

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1
Department of Pediatrics, Jichi Medical School, Tochigi, Japan.

Abstract

Direct enzymatic assay of urinary sulfated bile acids is a sensitive, rapid, minimally invasive, and convenient method of detecting cholestasis in young infants. It may replace measurement of serum direct bilirubin for selective screening for biliary atresia and neonatal hepatitis syndrome at 1 month of age.

PMID:
8765633
[Indexed for MEDLINE]

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