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Behav Brain Res. 1996 May;77(1-2):223-5.

The GABAB receptor antagonist CGP 36,742 and the nootropic oxiracetam facilitate the formation of long-term memory.

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Pharmaceutical Research Department, CIBA Ltd., Basel, Switzerland.


The memory-enhancing effects of a single treatment with the GABAB antagonist CGP 36,742 (10 mg/kg) or the nootropic agent oxiracetam (100 mg/kg) given immediately after a learning experience ('post-trial') remain detectable for at least 4 months thereafter. This indicates that in all probability these substances facilitate the formation of the long-term memory trace.

[Indexed for MEDLINE]

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