Send to

Choose Destination
Brain Res Mol Brain Res. 1995 Dec 1;34(1):166-72.

Localization of Fas antigen mRNA induced in postischemic murine forebrain by in situ hybridization.

Author information

Fifth Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya, Japan.


The expression of mRNA for the Fas antigen, a membrane-associated protein mediating apoptosis, was localized by in situ hybridization histochemistry in murine brains following 30 min of global cerebral ischemia. Six hours following the ischemia, many labeled cells were detected anew throughout the brain. The hybridization was seen in the small neural cells and in the cells along the walls of the ventricles and vessels, and became undetectable 24 h following the ischemia. These results suggest that the Fas antigen is expressed in the neuron, glia and periventricular cells of the post-ischemic brain.

[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center