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Graefes Arch Clin Exp Ophthalmol. 1996 Jan;234(1):67-8.

The use of tissue plasminogen activator in post-traumatic total hyphaema.

Author information

1
Department of Opthalmology, Oulu University Hospital, Finland.

Abstract

BACKGROUND:

We wanted to evaluate whether intracameral injection of tissue plasminogen activator (tPA) is useful in managing traumatic hyphaema.

METHODS:

Two eyes with total hyphaema after a severe penetrating injury were treated with a single intracameral injection of 25 micrograms of tPA 5 and 14 days after the injury, respectively.

RESULTS:

Most of the blood coagulum dissolved within 24 h, and in one of the two eyes the intraocular pressure decreased from 45 to 8 mmHg. The other eye was hypotonic. No re-bleeding or complications related to the use of tPA were noticed.

CONCLUSION:

The results in these two cases suggest that tPA is a useful adjunct in managing total hyphaema.

PMID:
8750854
DOI:
10.1007/bf00186522
[Indexed for MEDLINE]

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