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Curr Opin Cell Biol. 1996 Jun;8(3):358-64.

Transcriptional repression in development.

Author information

1
Department of Biology, University of California, San Diego, La Jolla 92093-0347, USA.

Abstract

It is becoming increasingly clear that transcriptional repression is at least as important as transcriptional activation for establishing cell-type specific patterns of gene expression during embryogenesis. Recent studies in Drosophila suggest that repressors fall into two categories, short-range and long-range repressors. The former permit enhancer autonomy in modular promoters, whereas the latter function in a dominant fashion to silence multiple enhancers.

PMID:
8743887
DOI:
10.1016/s0955-0674(96)80010-x
[Indexed for MEDLINE]

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