Send to

Choose Destination
Am J Med Genet. 1996 Jan 22;61(3):264-8.

Blood group chimerism in human multiple births is not rare.

Author information

Blood Transfusion Department, University Hospital St. Radboud, Nijmegen, Netherlands.


Twin blood group chimerism seems to be very rare in humans. The 30-40 previously reported cases usually were found by mere coincidence during routine blood grouping in hospitals or blood banks. Usually in these cases frank blood group mixtures of, for example, 50/50%, 25/75%, or 5/95% at most were seen. Smaller percentages are very difficult to notice during routine work-up. Using a sensitive fluorescence technique (sensitivity > 0.01%) we detected blood group chimerism in 32/415 (8%) twin pairs and 12/57 (21%) triplet pairs, respectively, which is a higher incidence than reported previously.

Supplemental Content

Loading ...
Support Center