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J Ethnopharmacol. 1996 Jun;52(2):101-5.

Diuretic and natriuretic effects of chromatographically purified fraction of garlic (Allium sativum).

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Department of Physiology, Faculty of Biological Sciences, Universidad de ConcepciĆ³n, Chile.


The intravenous administration of chromatographically purified fractions of garlic (2, 4 and 6 micrograms/kg dry weight) to anaesthetized rabbits elicits dose-dependent diuretic-natriuretic responses which reach a maximum 60 min after injection, and return to basal levels after 90 min. A gradual decrease in heart rate, but not in arterial blood pressure was observed during the course of the experimental periods. The electrocardiogram was not affected.

[Indexed for MEDLINE]

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