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CLAO J. 1996 Apr;22(2):122-6.

Non-contact specular microscopic observation for early response of corneal endothelium after contact lens wear.

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1
Department of Ophthalmology, School of Medicine, Juntendo University, Tokyo, Japan.

Abstract

PURPOSE:

Contact lenses induce short- and long-term corneal endothelial changes, including endothelial blebs. The endothelial bleb is a reversible, short-term response found on the corneal endothelium after lens wear. We used non-contact specular microscopy to observe endothelial blebs occurring with different types of contact lenses.

METHODS:

We observed the time course, frequency, and location of endothelial blebs in 11 eyes of 9 contact lens wearing patients. Eight types of contact lenses with various oxygen transmissibilities (Dk/L) were used in the study.

RESULTS:

Blebs were observed in the central cornea in patients with polymethylmethacrylate and rigid gas permeable contact lenses, while blebs in the central to mid-peripheral cornea were seen in patients wearing soft contact lenses.

CONCLUSIONS:

Although the number of blebs vary by individual patient, there appears to be an inverse correlation between the number of blebs and the Dk/L of the contact lens.

PMID:
8728619
[Indexed for MEDLINE]
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