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Trends Microbiol. 1996 May;4(5):185-91.

Bacterial transferrin and lactoferrin receptors.

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Dept of Microbiology and Infectious Diseases, Faculty of Medicine, University of Calgary, Alberta, Canada.


Pathogenic members of the Neisseriaceae and Pasteurellaceae express outer-membrane receptor proteins involved in the direct assimilation of iron from the host glycoproteins transferrin and lactoferrin. The critical requirement of iron for growth suggests that this function is an important component of colonization and infection. A model describing this novel process is presented.

[Indexed for MEDLINE]

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