Format

Send to

Choose Destination
See comment in PubMed Commons below
Antimicrob Agents Chemother. 1996 Jun;40(6):1552-4.

Eucaryotic cells protect Borrelia burgdorferi from the action of penicillin and ceftriaxone but not from the action of doxycycline and erythromycin.

Author information

  • 1Unité des Rickettsies, Faculté de Médecine, Centre National de la Recherche Scientifique, Marseille, France.

Abstract

Despite appropriate antibiotic treatment, Lyme disease patients may have relapses or may develop chronic manifestations. The intracellular location of Borrelia burgdorferi suggests that antibiotics that penetrate cells will have greater efficiency. Doxycycline or erythromycin was more effective than penicillin or ceftriaxone in killing B. burgdorferi when the organism was grown in the presence of eucaryotic cells.

PMID:
8726038
PMCID:
PMC163368
[PubMed - indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for PubMed Central
    Loading ...
    Support Center