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Planta Med. 1996 Feb;62(1):60-1.

Effects of some components of the essential oil of chamomile, Chamomilla recutita, on histamine release from rat mast cells.

Author information

1
Institut für Pharmazeutische Biologie, Ernst-Moritz-Arndt Universität Greifswald, Germany.

Abstract

The influence of three compounds of the essential oil of Chamomilla recutita (L.) Rauschert on the protamine sulphate-provoked degranulation of mast cells from Lewis-1a rats was investigated. The effect was determined by measuring histamine liberation fluorometrically. Chamazulene and (-)-alpha-bisabolol had no distinct effects. The en-yne dicycloether partly inhibited the degranulation in concentrations above 10(-4) M.

PMID:
8720389
DOI:
10.1055/s-2006-957799
[Indexed for MEDLINE]

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