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Clin Lab Haematol. 1995 Sep;17(3):243-6.

Acute non-lymphoblastic leukaemia with t(16;21): case report with a review of the literature.

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Division of Structural Studies, Medical Research Council Laboratory of Molecular Biology, Cambridge, UK.


A rare case of acute non-lymphoblastic leukaemia with chromosomal t(16;21)(p11;q22) translocation was studied at the molecular level. Most of the previous reports about the translocation have been described at a karyotypic level. Blast cells of this patient expressed the TLS-ERG chimeric mRNA. The clinical, morphological, karyotypic, and immunohistochemical aspects of this leukaemia are also presented with a review of the literature.

[Indexed for MEDLINE]

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